Electrospun biodegradable nanofibers scaffolds for bone tissue engineering
نویسندگان
چکیده
منابع مشابه
Biodegradable nanofibers-reinforced microfibrous composite scaffolds for bone tissue engineering.
Native bone extracellular matrix (ECM) is a complex hierarchical fibrous composite structure, resulting from the assembling of collagen fibrils at several length scales, ranging from the macro to the nanoscale. The combination of nanofibers within microfibers after conventional reinforcement methodologies seems to be a feasible solution to the rational design of highly functional synthetic ECM ...
متن کاملElectrospun Nanofibers in Tissue Engineering
The field of tissue engineering and regenerative medicine is a fast growing scientific field. Many diseases and injuries that result in the loss of organ or tissue functions currently lack treatments which restore those functions and the patient to a desirable quality of life. Many current treatments could greatly benefit from incorporation of bioengineered organs and tissues, and investigation...
متن کاملElectrospun nanofibers for neural tissue engineering.
Biodegradable nanofibers produced by electrospinning represent a new class of promising scaffolds to support nerve regeneration. We begin with a brief discussion on the electrospinning of nanofibers and methods for controlling the structure, porosity, and alignment of the electrospun nanofibers. The methods include control of the nanoscale morphology and microscale alignment of the nanofibers, ...
متن کاملAligned and random nanofibrous nanocomposite scaffolds for bone tissue engineering
Aligned and random nanocomposite nanofibrous scaffolds were electrospun from polycaprolactone (PCL), poly (vinyl alcohol) (PVA) and hydroxyapatite nanoparticles (nHA). The morphology and mechanical characteristics of the nanofibers were evaluated using scanning electron microscopy and tensile testing, respectively. Scanning electron microscopy revealed fibers with an average diameter of 123 ± 3...
متن کاملBiodegradable Polymer-bioceramic Composite Scaffolds for Bone Tissue Engineering
Critical size bone defects due to trauma or disease are very difficult to repair via the natural growth of the host bone. Therefore, these defects must be filled with a bridging material (scaffold), which should also, in combination with relevant cells and signalling molecules, promote the regeneration of new bone tissue. In this context, bone regeneration is one of the most attractive areas in...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Applied Polymer Science
سال: 2015
ISSN: 0021-8995
DOI: 10.1002/app.42883